While the cause of Whitney Houston’s death may not be known for weeks, the 48-year-old singer reportedly had a prescription for Xanax and a history of alcohol and drug abuse, checking into rehab centers at least three times during her career.

Found dead in a bathtub Feb. 11, one prevalent theory for her cause of death is a drug/alcohol combination overdose.

Toxology reports can take weeks to complete, but it is known that a combination of Xanax and alcohol can be deadly, said Dr. Marvin Seppala, chief medical officer at Hazelden, a preeminent treatment center for alcohol and other drug addiction.

The anti-anxiety drug alprazolam, the generic name for Xanax, is classified as a benzodiazepine. Benzodiazepines are sedatives that work by binding to part of the brain’s natural tranquilizers, or gamma amino butyric acids, to increase your natural calming ability.

They work quickly, often in 15 minutes — and are highly addictive. The effects last just a few hours. Alprazolam is also the eighth-most prescribed drug in the United States in 2010, according to the New York Times.

“It’s often used for stage fright or other types of anxiety; however, it’s abused a great deal and has the potential for addiction,” Seppala said, especially if someone has a genetic predisposition for addiction. “Tolerance develops quickly if it’s used on a regular basis.”

When mixed with alcohol, the anti-anxiety drug’s effects can be intensified, resulting in greater intoxication. Another risk, though, is respiratory depression. Both substances can cause your heart rate to slow and impair your breathing, putting those who overdose at risk of death.

The combination of alcohol and benzodiazepines have a calming function in the brain, slowing down some of the brain’s functions, Seppala said.

“They cause the control mechanism of the respiratory system to slow down and ultimately stop,” he said.

Most patients checking in for rehab from the drug fall into two groups, Seppala said:

“One group never uses it addictively, but needs help getting off because they’ve built up tolerance,” he said. “The other group is mixing it with all kinds of other stuff: opiates, marijuana, alcohol, and that complicates the withdrawal and the whole picture.”

The longer Xanax and similar drugs are taken, the less effective they become. Withdrawal effects are unpleasant, including headaches, insomnia, depression — and more nervousness.

Abuse of alprazolam has become so rampant and demand for the drug so high that a clinic in Louisville, Ky., decided to stop writing new prescriptions for the drug last September. And in 2010, the Centers for Disease Control and Prevention reported an 89 percent increase in emergency room visits nationwide related to non-medical benzodiazepine use between 2004 and 2008.

The increase in Xanax prescriptions, Seppala said, can be attributed to patients expecting medication and doctors being willing to hand it out.

There are better medications for stage fright, Seppala said.

“There’s a type of antihypertensive beta blockers that are non-addicting and reduce anxiety,” he said. “They’re used for performance anxiety; for example, when a cellist or violinist who plays great in practice but develops a slight tremor on stage because of anxiety.”

Houston had been hoping to revive her career this year with a possible comeback album, the New York Times reported. In the days before her death, her behavior appeared erratic, wearing mismatched clothes with wet hair and bursting on the set of a television interview with Clive Davis. Slurred speech and behavior often associated with being drunk are also typical of high doses of Xanax, Seppala said.

“I know there are reports that she maybe was drowned, or did she overdose, but we won’t make a final determination until all the tests are in,” said Ed Winter of the Los Angeles coroner’s office at a news conference on Sunday.

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The Campbellsville Police Department responded Saturday, February 11 at 9:35am to a request for a “welfare check” from Matt Wayn of Cincinnati, Ohio reporting he had not heard from his mother, Elizabeth Arimsmier. Ms. Arimsmier, 78, resided at 105 Daisy Drive in Campbellsville. Officers responded to the address Saturday morning at 9:30 AM and did not receive a response. Entry was gained and the victim – Ms. Arimsmier was found unresponsive. The Coroner was notified and pronounced the victim deceased. An autopsy was performed by the State Medical Examiner’s Office in Louisville on Sunday, February 12th, which determined the victim died as a result of blunt force trauma sustained days earlier.

The investigation continued Sunday resulting in the arrest of Jessie James Durham, age 20 of Campbellsville. Durham is the great-grandson of the victim. Durham was charged with Murder and lodged in the Taylor County Regional Jail.

The investigation is continuing by Officer David Tucker.

Rumor has it the grandson has confessed to murdering his grandmother through blunt force trauma brought on by smashing his grandmother repeatedly in the head with a hammer.

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Scientists Claim Time is Literally Running Out


Scientists have come up with the radical suggestion that the universe’s end may come not with a bang but a standstill – that time could be literally running out and could, one day, stop altogether.

The idea that time itself could cease to be in billions of years – and everything will grind to a halt – has been set out by Professor José Senovilla, Marc Mars and Raül Vera of the University of the Basque Country, Bilbao, and University of Salamanca, Spain.

The motivation for this radical end to time itself is to provide an alternative explanation for “dark energy” – the mysterious antigravitational force that has been suggested to explain a cosmic phenomenon that has baffled scientists.

A decade ago, astronomers noticed that distant supernovae – exploding stars on the very fringes of the universe – seemed to be moving faster than those nearer to the centre, suggesting that they were accelerating as they shot through space.

Dark energy was suggested as a possible means of powering this acceleration of the expansion of the cosmos.

The problem is that no-one has any idea what dark energy is or where it comes from, and theoreticians around the world have been scrambling to find out what it is, or get rid of it.

The team’s proposal, which will be published in the journal Physical Review D, does away altogether with dark energy. Instead, Prof Senovilla says, the appearance of acceleration is caused by time itself gradually slowing down, like a clock that needs winding.

“We do not say that the expansion of the universe itself is an illusion,” he explains. “What we say it may be an illusion is the acceleration of this expansion – that is, the possibility that the expansion is, and has been, increasing its rate.”

Instead, if time gradually slows “but we naively kept using our equations to derive the changes of the expansion with respect of ‘a standard flow of time’, then the simple models that we have constructed in our paper show that an “effective accelerated rate of the expansion” takes place.”

While the change would be infinitesimally slow from an ordinary human perspective, from the grand perspective of cosmology – in which scientists study ancient light from suns that shone billions of years ago – this temporal slowing could be easily measured.

Astronomers are able to discern the expansion speed of the universe using the so-called “red shift” technique.

The principle is the same as that of an ambulance siren which gets higher as it comes towards the listener but lower as it moves away. Similarly, a star moving away appears redder in colour than one moving towards us.

Scientists look for exploding stars – supernovae – of certain types that provide a benchmark to work against.

However, the accuracy of these measurements depend on time remaining invariable throughout the universe.
If time is indeed slowing down, so that according to this new suggestion our solitary time dimension is slowly turning into a new space dimension, then the far-distant, ancient stars seen by cosmologists would therefore, from our perspective, look as though they were accelerating.

“Our calculations show that we would think that the expansion of the universe is accelerating,” says Prof Senovilla.

The group bases its idea on one particular variant of superstring theory, a so called theory of everything, in which our universe is confined to the surface of a membrane, or brane, floating in a higher-dimensional space, known as the “bulk”.

In some number of billions of years, time would cease to be time altogether – and everything will stop.
“Then everything will be frozen, like a snapshot of one instant, forever,” Prof Senovilla tells New Scientist magazine. “Our planet will be long gone by then.”

However, he adds that the team is only assuming there is one dimension of time. Itzhak Bars of the University of Southern California in Los Angeles has put forward the bizarre suggestion that there are two dimensions of time, not the one that we are all familiar with.

Prof Senovilla says: “One thing that is definitely not included in our models is the possibility of having more than one time dimension.”

While the theory is outlandish, it is not without support. Prof Gary Gibbons, a cosmologist at Cambridge University, believes the idea has merit. “We believe that time emerged during the Big Bang, and if time can emerge, it can also disappear – that’s just the reverse effect,” he says.

“The wonderful thing about these explanations is that, strange as they sound, the Large Hadron Collider could provide evidence for extra dimensions in the universe,” comments Dr Brian Cox of Manchester University, referring to the atom smasher in Geneva that will start up next year.

“If that happens, then these kind of theories will move out of the realm of speculation and into the mainstream.”

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The researchers have for the first time generated crucial types of human brain cells in the laboratory by reprogramming skin cells, which they say could speed up the hunt for new treatments for conditions such as Alzheimer’s disease, epilepsy and stroke.

Until now it has only been possible to generate tissue from the cerebral cortex, the area of the brain where most major neurological diseases occur, by using controversial embryonic stem cells, obtained by the destruction of an embryo.

This has meant the supply of brain tissue available for research has been limited due to the ethical concerns around embryonic stem cells and shortages in their availability.

Scientists at the University of Cambridge, however, now insist they have overcome this problem after showing for the first time that it is possible to re-programme adult human skin cells so that they develop into neurons found in the cerebral cortex.

Initially brain cells grown in this way could be used to help researchers gain a better understanding of how the brain develops, what goes wrong when it is affected by disease and it could also be used for screening new drug treatments.

Eventually they hope the cells could also be used to provide healthy tissue that can be implanted into patients to treat neurodegenerative diseases and brain damage.

Dr Rick Livesey, who led the research at the University of Cambridge’s Gurdon [corr] Institute, said: “The cerebral cortex makes up 75% of the human brain, is where all the important processes that make us human take place. It is, however, also the major place where disease can occur.

“We have been able to take reprogrammed skin cells so they develop into brain stem cells and then essentially replay brain development in the laboratory.

“We can study brain development and what goes wrong when it is affected by disease in a way we haven’t been able to before. We see it as a major breakthrough in what will now be possible.”

The cerebral cortex is the part of the brain that is responsible for most of the major high-level thought processes such as memory, language and consciousness.

While human brain cells have been created from stem cells before, this has relied upon embryonic stem cells. Attempts to make them from skin cells have produced neurons that are not found in the cerebral cortex.

Dr Livesey and his colleagues were able to create the two major types of neuron that form the cerebral cortex from reprogrammed skin cells and show that they were identical to those created from the more controversial embryonic stem cells.

Dr Livesey, whose findings are published in the journal Nature Neuroscience, said this may eventually lead to new treatments for patients where damaged tissue could be replaced by brain cells grown in the laboratory from a sample of their skin.

He said: “You don’t need to rebuild damage to recover function as the brain is quite good at recovering itself – it does this after stroke for example. However, it may be possible to give it some extra real estate that it can use to do this.

“We can make large numbers of cerebral cortex neurons by taking a sample of skin from anybody, so in principal it should be possible to put these back into the patients.”

Dr Simon Ridley, head of research at Alzheimer’s Research UK, which funded the study alongside the Wellcome Trust, added: “Turning stem cells into networks of fully functional nerve cells in the lab holds great promise for unravelling complex brain diseases such as Alzheimer’s.”

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President Obama has frequently justified his policies—and judged their outcomes—in terms of equity, justice and fairness. That raises an obvious question: How does our existing system—and his own policy record—stack up according to those criteria?

Is it fair that the richest 1% of Americans pay nearly 40% of all federal income taxes, and the richest 10% pay two-thirds of the tax?

Is it fair that the richest 10% of Americans shoulder a higher share of their country’s income-tax burden than do the richest 10% in every other industrialized nation, including socialist Sweden?

Is it fair that American corporations pay the highest statutory corporate tax rate of all other industrialized nations but Japan, which cuts its rate on April 1?

Is it fair that President Obama sends his two daughters to elite private schools that are safer, better-run, and produce higher test scores than public schools in Washington, D.C.—but millions of other families across America are denied that free choice and forced to send their kids to rotten schools?

Is it fair that Americans who build a family business, hire workers, reinvest and save their money—paying a lifetime of federal, state and local taxes often climbing into the millions of dollars—must then pay an additional estate tax of 35% (and as much as 55% when the law changes next year) when they die, rather than passing that money onto their loved ones?

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Is it fair that Treasury Secretary Tim Geithner, former Democratic Senate Majority Leader Tom Daschle, former Ways and Means Chairman Charlie Rangel and other leading Democrats who preach tax fairness underpaid their own taxes?

Is it fair that after the first three years of Obamanomics, the poor are poorer, the poverty rate is rising, the middle class is losing income, and some 5.5 million fewer Americans have jobs today than in 2007?

Is it fair that roughly 88% of political contributions from supposedly impartial network television reporters, producers and other employees in 2008 went to Democrats?

Is it fair that the three counties with America’s highest median family income just happen to be located in the Washington, D.C., metro area?

Is it fair that wind, solar and ethanol producers get billions of dollars of subsidies each year and pay virtually no taxes, while the oil and gas industry—which provides at least 10 times as much energy—pays tens of billions of dollars of taxes while the president complains that it is “subsidized”?

Is it fair that those who work full-time jobs (and sometimes more) to make ends meet have to pay taxes to support up to 99 weeks of unemployment benefits for those who don’t work?

Is it fair that those who took out responsible mortgages and pay them each month have to see their tax dollars used to subsidize those who acted recklessly, greedily and sometimes deceitfully in taking out mortgages they now can’t afford to repay?

Is it fair that thousands of workers won’t have jobs because the president sided with environmentalists and blocked the shovel-ready Keystone XL oil pipeline?

Is it fair that some of Mr. Obama’s largest campaign contributors received federal loan guarantees on their investments in renewable energy projects that went bust?

Is it fair that federal employees receive benefits that are nearly 50% higher than those of private-sector workers whose taxes pay their salaries, according to the Congressional Budget Office?

Is it fair that soon almost half the federal budget will take income from young working people and redistribute it to old non-working people, even though those over age 65 are already among the wealthiest Americans?

Is it fair that in 27 states workers can be compelled to join a union in order to keep their jobs?

Is it fair that nearly four out of 10 American households now pay no federal income tax at all—a number that has risen every year under Mr. Obama?

Is it fair that Boeing, a private company, was threatened by a federal agency when it sought to add jobs in a right-to-work state rather than in a forced-union state?

Is it fair that our kids and grandkids and great-grandkids—who never voted for Mr. Obama—will have to pay off the $5 trillion of debt accumulated over the past four years, without any benefits to them?

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Breaking the Brain Code


You might not realize it, but your brain is a code-cracking machine.

For emaxlpe, it deson’t mttaer in waht oredr the ltteers in a wrod aepapr, the olny iprmoatnt tihng is taht the frist and lsat ltteer are in the rghit pcale. The rset can be a toatl mses and you can sitll raed it wouthit pobelrm.

S1M1L4RLY, Y0UR M1ND 15 R34D1NG 7H15 4U70M471C4LLY W17H0U7 3V3N 7H1NK1NG 4B0U7 17.

Passages like these have been bouncing around the Internet for years. But how do we read them? And what do our incredibly low standards for what’s legible say about the way our brains work?

According to Marta Kutas, a cognitive neuroscientist and the director of the Center for Research in Language at the University of California, San Diego, the short answer is that no one knows why we’re so good at reading garbled nonsense. But they’ve got strong suspicions.

“My guess is that context is very, very, very important,” Kutas told Life’s Little Mysteries.

We use context to pre-activate the areas of our brains that correspond to what we expect next, she explained. For example, brain scans reveal that if we hear a sound that leads us to strongly suspect another sound is on the way, the brain acts as if we’re already hearing the second sound. Similarly, if we see a certain collection of letters or words, our brains jump to conclusions about what comes next. “We use context to help us perceive,” Kutas said. [6 Fun Ways to Exercise Your Brain]

It’s not a perfect system, however. In the above passages, Kutas suspects that you probably didn’t get every single word right just from knowing what came before it. You onlythought you were reading the passage perfectly, because you automatically (and subconsciously) went back and filled in any gaps in your knowledge based on subsequent context — the words that came later.

Additionally, in the case of the first example (the words with jumbled middle letters), it helps that your brain processes all the letters of a word at once, rather than one at a time. Thus, the letters “serve as contexts for each other,” Kutas said.

In the case of the second passage (with the numbers in place of some letters), a 2007 study by cognitive scientists in Spain found that reading such passages barely activates the brain areas that correspond to digits. This suggests that the letter-like appearance of the digits, as well as their context, has a stronger influence on our brains than their actual status as digits. The researchers think some sort of top-down feedback mechanism (our consciences telling our sensory processors what to do, sort of) normalizes the visual input, allowing us to ignore the funny bits and read the passage with ease.

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Alien planets might experience tidal forces powerful enough to remove all their water, leaving behind hot, dry worlds like Venus, researchers said.

These findings might significantly affect searches for habitable exoplanets, scientists explained. Although some planets might dwell in regions around their star friendly enough for life as we know it, they could actually be lifelessly dry worlds.

The tides that we experience on Earth are caused by the gravitational pull of the moon and sun. Our tides are nothing compared to what we see elsewhere in the solar system — the gravitational pull Europa experiences from Jupiter leads to tidal forces roughly 1,000 times stronger than what Earth feels from our moon, flexing and heating Europa.

Heat is a major factor in how capable a planet might be of supporting life as we know it. What scientists call the habitable zone of a star is defined by whether liquid water can survive on its surface, given that life exists virtually wherever there is liquid water on Earth.

Too far from a star, and the lack of light makes a world too cold, freezing all its water; too close to a star, and all that blazing heat makes a world too hot, boiling all of its water off in what is known as a runaway greenhouse effect.

Venus is often thought to have experienced a runaway greenhouse effect. Eventually, solar radiation broke up all of Venus’s vaporized water into hydrogen and oxygen, which leaked away from the planet entirely.

Now scientists find that stellar heat is not the only thing that can trigger a runaway greenhouse climate catastrophe. Tidal heating can too, for what they call “tidal Venuses.”

“This has fundamentally changed the concept of a habitable zone,” said researcher Rory Barnes, a planetary scientist and astrobiologist at the University of Washington. “We figured out you can actually limit a planet’s habitability with an energy source other than starlight.”

Tidal Venuses could not occur around stars like our sun because the effects of tides fall off rapidly with distance, Barnes noted. For a planet to experience tidal heating from a star like our sun, it would have to be so close in that heat from its light would render it uninhabitable even without any tidal heating.

However, tidal Venuses could occur around dimmer and much less massive bodies — main-sequence stars less than a third the mass of our sun, for instance, or failed stars known as brown dwarfs, or dead stars such as white dwarfs. These bodies have been of interest to astrobiologists because their dim nature means their habitable zones are theoretically very close. Planets near their stars eclipse them more often, making them easier to detect than planets that are farther away — as such, researchers had thought dim, low-mass stars could be ideal places to find habitable worlds.

After a tidal Venus loses all its water and becomes uninhabitable, the tides could alter its orbit so that it no longer experiences tidal heating. As such, it might no longer appear like a tidal Venus, but look just like any other world in its star’s habitable zone, fooling researchers into thinking it is potentially friendly for life, even though it has essentially been sterilized.

As terrestrial worlds are found around dim bodies, factoring these findings into searches for habitable exoplanets could result in scientists wasting less time on dry worlds. “As candidates for habitable worlds are found, tidal effects need careful attention,” Barnes said. “You don’t want to waste time on desiccated planets.”

Barnes noted that more work needed to be done analyzing how the effects of tidal heating might actually manifest themselves. “In our solar system, the largest amount of tidal heating is with Jupiter’s moon Io, which experiences 2 watts per square meter on its surface,” Barnes said. “We’re trying to see if tidal heating can generate 300 watts per square meter on a planet’s surface, and it’s still unclear if planets will actually behave this way — maybe there’s a saturation point where tidal heating can’t reach tidal Venus levels. Planets are complicated beasts, and it’s not always obvious how they will act.”

“We’ll have to be careful when assessing objects that are very near dim stars, where the tides are much stronger than we feel on present-day Earth,” said planetary scientist Norman Sleep at Stanford University, who did not take part in this research.”Even Venus now is not substantially heated by tides, and neither is Mercury.”

“The only good example of this we might have had like this in the solar system is Earth early in its history soon after the moon-forming impact, where tidal heating from the moon was significant for 10 million years or so, enough for a brief runaway greenhouse,” Sleep added. “Eventually the moon moved far enough away for tidal heating to decrease.”

It could be that instead of triggering a runaway greenhouse effect, tidal heating might actually warm otherwise frigid planets enough for them to have liquid water on their surface, Sleep added. “Whether or not something could stay habitable or not through this mechanism is unclear to me,” he cautioned.

The next step “is to consider how multi-planet systems affect the results,” Barnes said. “We’ve looked at just a single star and a single planet evolving together, but when you have additional planets, you introduce gravitational perturbations, and how will that affect orbits and tidal heating and habitability? They could very well increase the threat of catastrophic tidal heating.”

Barnes and his colleagues detailed their findings Jan. 11 at the annual meeting of the American Astronomical Society in Austin, Texas.

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Give a male garter snake a taste of estrogen and watch out, as the hormone turns these lads into the sexiest thing on the block, attracting dozens of other males eager to mate.

The finding, published in the Journal of Experimental Biology, has implications for understanding the environmental impact of compounds that mimic the effect of estrogen, found in some chemicals and pesticides.

Estrogen, the researchers found, is key to a female’s release of pheromones and thus, reproduction.

Here’s how it works: For the red-sided garter snake, picking up a mate takes but a second and a flick of the tongue. When a male detects a possible mate nearby, he licks the female with a quick flick of his tongue. The chemical cues, called pheromones, exuded by the females are so strong it takes but an instant, the researchers say, for the male to determine the other snake’s species, sex, population, reproduction condition, size and age. In fact, the males are totally dependent on these pheromones for snake reproduction.

Every spring, tens of thousands of these garter snakes emerge from their limestone caves north of Manitoba, Canada, for mating. Intense competition ensues, as males swarm (and tongue) female snakes in an effort to be the first to mate with her. The frenzy appears as twisting balls of snakes called mating balls.

The males tend to choose the larger, more mature gals, because these females can produce more babies; they also have a slightly different chemical signature in their pheromones. While young, small females do get action, they aren’t the preferred mates.

Once they mate, the females emit a different pheromone, confirming “no more sex,” causing other males to lose interest and leave the area.

In the new study, the researchers implanted male garter snakes in their natural environment, each with a capsule that raised their estrogen levels to approximately match those of female snakes. After one year of these estrogen supplements, the male snakes started secreting a pheromone that seemed to cause other males to swarm to them, forming clumps of writhing snakes tangled together. Apparently, the estrogen caused the males to secrete “female” pheromones.

“We thought this might work, but we were surprised the results were so compelling,” study researcher Robert Mason, a professor of zoology at Oregon State University, said in a statement. “The amount of estrogen the male snakes received was nothing unusual, just about what a normal female would produce.”

The other males, in fact, preferred the male snakes with boosted estrogen levels to the small female snakes, the researchers found.

When the researchers stopped giving the males estrogen, they reverted back to their normal behaviors.

This work was supported by the National Science Foundation and the U.S. Environmental Protection Agency.

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Agovernment minister in Zimbabwe says work has stopped on new reservoirs because workers have been scared off by mermaids, a report has said.

According to orangenews.com, Minister of Water Resources Samuel Sipepa Nkomo reportedly told a parliamentary committee that terrified workers were refusing to return to the sites, near the towns of Gokwe and Mutare.

He said the only way to solve the problem was to brew traditional beer and carry out rites to appease the spirits.

“All the officers I have sent have vowed not to go back there,” Zimbabwe’s state-approved Herald newspaper quoted him as saying.

The senior politician allegedly said mermaids were also present in other reservoirs around the country.

The building of the reservoirs is long overdue, but is considered essential if Zimbabwe is to provide adequate water for its population and boost agricultural production.

The belief in mermaids and other mythical creatures is widespread in the country, where many people combine a Christian faith with traditional beliefs.

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Egg Laying Rooster Shocks Scientists


Chinese scientists are investigating a bizarre case in which a cockerel apparently started laying eggs after all the hens were eaten.

The birds owner Huang Li, 47, kept the rooster together with seven hens on his small farm at Chumiao village, Mengcheng city, in central China’s Anhui province.

He said that his family had been gradually eating the chickens over winter until only the rooster was left – and he was amazed when he went into the cage the next day to discover an egg.

He said: “I thought it was a joke and that one of my neighbours had put the egg in there for fun. But the next day there was another egg and so on the third day I waited – and was amazed when I saw that the rooster laid an egg.”

He said word quickly spread to the local TV station which did a story on the egg laying rooster and after that scientists from the local agricultural ministry office turned up and borrowed the rooster to carry out tests.

He said: “They want to find out if it was a hen all the time that simply looked like a rooster or whether it actually changed to become a hen as a result of the fact that all the females had vanished.

“All I can say is that it did a good job waking us up every morning like every other rooster and it certainly treated the hens as if it was a rooster.”

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